Miller S, Riessen R
Radiologische Universitätsklinik Tübingen.
Rofo. 2005 Nov;177(11):1497-505. doi: 10.1055/s-2005-858543.
According to the WHO classification, cardiomyopathies are a group of diseases which are associated with myocardial dysfunction and can be classified either as primary or secondary cardiomyopathies. Genetic disorders have been identified in certain primary cardiomyopathies, however often the etiology remains unknown. The term "secondary cardiomyopathy" is used to specify diseases with the clinical indications of a cardiomyopathy, but can be attributed to a certain pathophysiological mechanism such as exposure to toxic substances, metabolic syndromes or systemic diseases. Based on morphological and functional criteria, primary cardiomyopathies are divided into dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), arrhythmogenic right ventricular cardiomyopathy (ARVC) and restrictive cardiomyopathy (RCM). During the last two decades MR imaging has emerged to a well established diagnostic tool for the understanding and treatment of cardiomyopathies. Morphological and functional information can be achieved with a high level of accuracy and reproducibility. Tissue alteration of the myocardium can be detected assessing regional contrast enhancement, T1- and T2-signal intensities and chemical shift phenomena. This article describes characteristic aspects of MR imaging for the diagnosis of primary and secondary cardiomyopathies.
根据世界卫生组织的分类,心肌病是一组与心肌功能障碍相关的疾病,可分为原发性或继发性心肌病。在某些原发性心肌病中已发现遗传疾病,但病因往往仍不清楚。“继发性心肌病”一词用于指定具有心肌病临床指征的疾病,但可归因于某种病理生理机制,如接触有毒物质、代谢综合征或全身性疾病。根据形态学和功能标准,原发性心肌病分为扩张型心肌病(DCM)、肥厚型心肌病(HCM)、致心律失常性右室心肌病(ARVC)和限制型心肌病(RCM)。在过去二十年中,磁共振成像已成为一种成熟的诊断工具,用于心肌病的诊断和治疗。形态学和功能信息可以以高度的准确性和可重复性获得。通过评估局部对比增强、T1和T2信号强度以及化学位移现象,可以检测到心肌的组织改变。本文描述了磁共振成像在原发性和继发性心肌病诊断中的特征性表现。