通过胸腔穿刺术诊断小儿伯基特淋巴瘤

Diagnosis of Burkitt lymphoma in pediatric patients by thoracentesis.

作者信息

McLean Thomas W, Farber Rebecca S, Lewis Zachary T, Wofford Marcia M, Pettenati Mark J, Pranikoff Thomas, Chauvenet Allen R

机构信息

Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

出版信息

Pediatr Blood Cancer. 2007 Jul;49(1):90-2. doi: 10.1002/pbc.20683.

DOI:10.1002/pbc.20683

PMID:16302222

Abstract

The diagnosis of Burkitt lymphoma by thoracentesis has been rarely reported in the literature, particularly in children. From 1995 to 2004, we diagnosed six pediatric patients with mature B-cell neoplasms using thoracentesis as the initial diagnostic procedure. The cytology, immunophenotyping, and cytogenetic results of the pleural fluid cells were consistent with mature B-cell malignancies. We conclude that thoracentesis for the diagnosis of Burkitt lymphoma in children is safe, fast, and accurate. It should be strongly considered as an initial diagnostic procedure for pediatric patients with pleural effusions who are suspected of having B-cell malignancies.

摘要

通过胸腔穿刺术诊断伯基特淋巴瘤在文献中鲜有报道，尤其是在儿童中。1995年至2004年期间，我们通过胸腔穿刺术作为初始诊断程序诊断了6例患有成熟B细胞肿瘤的儿科患者。胸水细胞的细胞学、免疫表型和细胞遗传学结果与成熟B细胞恶性肿瘤一致。我们得出结论，胸腔穿刺术用于诊断儿童伯基特淋巴瘤是安全、快速且准确的。对于怀疑患有B细胞恶性肿瘤且有胸腔积液的儿科患者，应强烈考虑将其作为初始诊断程序。