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[结直肠癌筛查:最有效的策略是什么?]

[Screening for colorectal cancer: what is the most effective strategy?].

作者信息

Merzenich H, Giersiepen K, Kieschke J, Zeeb H

机构信息

Epidemiologisches Krebsregister Niedersachsen, Registerstelle Oldenburg.

出版信息

Gesundheitswesen. 2005 Nov;67(11):803-8. doi: 10.1055/s-2005-858793.

Abstract

Colorectal cancer is one of the most common cancers in Western countries. The long natural history of colorectal cancer provides opportunities for detection of early stage cancer and for prevention of cancer by removal of adenomas. An effective screening technique should significantly reduce morbidity and mortality in the population. Several tests are available to screen healthy subjects at average risk for colorectal cancer: total colonoscopy, combined sigmoidoscopy and faecal occult blood test (FOBT), FOBT alone. At the present time clear evidence for the most effective screening strategy is not available. Colonoscopy screening in Germany needs an adequate tool to evaluate the programme. Follow up is essential and cancer registries would be an important partner.

摘要

结直肠癌是西方国家最常见的癌症之一。结直肠癌漫长的自然病程为早期癌症的检测以及通过切除腺瘤预防癌症提供了机会。一种有效的筛查技术应能显著降低人群中的发病率和死亡率。有几种检测方法可用于筛查患结直肠癌平均风险的健康受试者:全结肠镜检查、乙状结肠镜检查与粪便潜血试验(FOBT)联合检查、单独的FOBT。目前尚无关于最有效筛查策略的确切证据。德国的结肠镜检查筛查需要一种合适的工具来评估该项目。随访至关重要,癌症登记处将是重要的合作伙伴。

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