角膜移植有多“安全”？关于角膜移植导致单纯疱疹病毒传播风险的探讨
[How "safe" is corneal transplantation? A contribution on the risk of HSV-transmission due to corneal transplantation].
作者信息
Robert P-Y R, Adenis J-P, Pleyer U
机构信息
clinique d'ophtalmologie, CHU Dupuytren, Limoges, Frankreich.
出版信息
Klin Monbl Augenheilkd. 2005 Nov;222(11):870-3. doi: 10.1055/s-2005-858849.
INTRODUCTION
We have attempted in this article to summarise the present literature on the risks of virus transmission via corneal transplantation, with special emphasize on Herpes simplex virus (HSV).
METHODS
We conducted a literature search from Medline.
RESULTS
HSV is now acknowledged as a cause of primary graft failure, and this entity has been attributed to donor-to-host HSV infection. HSV is the primary cause of graft failure, and may induce reactivation in the recipient in the dendritic form, or in atypical forms.
CONCLUSIONS
Corneal transplantation is a potential route for HSV infection as a possible transmittable disease which now has to be taken into consideration in eye banks.
引言
在本文中，我们试图总结目前关于通过角膜移植传播病毒风险的文献，特别着重于单纯疱疹病毒（HSV）。
方法
我们在医学文献数据库（Medline）中进行了文献检索。
结果
HSV现在被认为是原发性移植失败的一个原因，并且这种情况被归因于供体到宿主的HSV感染。HSV是移植失败的主要原因，并且可能在受者体内以树突状形式或非典型形式诱导病毒再激活。
结论
角膜移植是HSV感染作为一种可能的可传播疾病的潜在途径，眼库现在必须考虑到这一点。
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