Espié M, Hocini H, Cuvier C, Giacchetti S, Bourstyn E, de Roquancourt A
Centre des maladies du sein, hôpital Saint-Louis, Paris, France.
Gynecol Obstet Fertil. 2005 Dec;33(12):964-9. doi: 10.1016/j.gyobfe.2005.10.022. Epub 2005 Dec 1.
The incidence of lobular cancers in situ is increasing, especially in post-menopausal women. Whereas this form of disease was regarded for a long time as nothing but a risk factor of the occurrence of later infiltrating carcinoma, it now tends to represent a precancerous state whose progression to subsequent infiltrating carcinoma does not inevitably occur. The clinical and radiological diagnosis remains difficult and the choice of therapies varies according to teams, ranging from mere surveillance to mastectomy.
小叶原位癌的发病率正在上升,尤其是在绝经后女性中。尽管这种疾病形式长期以来一直被视为仅是后期浸润性癌发生的一个危险因素,但现在它往往代表一种癌前状态,其发展为后续浸润性癌并非不可避免。临床和放射学诊断仍然困难,治疗方法的选择因团队而异,从单纯监测到乳房切除术不等。