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梗阻性黄疸:儿童腹腔内非霍奇金淋巴瘤的一种不寻常的初始表现。

Obstructive jaundice: an unusual initial manifestation of intra-abdominal non-Hodgkin lymphoma in a child.

作者信息

Ugur Handan, Tacyildiz Nurdan, Yavuz Gulsan, Unal Emel, Sayili Ayse, Emir Suna, Kansu Aydan, Kuloglu Zarife, Bahar Kadir

机构信息

Pediatrics Department, Ankara University School of Medicine, Ankara, Turkey.

出版信息

Pediatr Hematol Oncol. 2006 Jan-Feb;23(1):87-90. doi: 10.1080/08880010500313363.

Abstract

Obstructive jaundice is an unusual manifestation of non-Hodgkin lymphomas in children. Although surgical drainage is one of the initial treatment choices in some cases, usually lymphomatous masses rapidly response to chemotherapy and jaundice decreases due to regression of the mass, without any surgical procedure. The authors report the case of a 16-year-old girl who presented with biliary obstruction due to a neoplasm involving the duodenum. Histological examination of the specimen, which was taken from the mass by endoscopic biopsy, revealed Burkitt lymphoma infiltrating the duodenum. Chemotherapy including cyclophosphamide was started immediately. In a few days, jaundice decreased rapidly by the shrinkage of the mass. Neither surgery nor percutaneous drainage were needed. In conclusion, biliary tract obstruction due to non-Hodgkin lymphoma can be effectively treated with chemotherapy alone without any surgical procedure.

摘要

梗阻性黄疸是儿童非霍奇金淋巴瘤的一种不常见表现。尽管在某些情况下手术引流是初始治疗选择之一,但通常淋巴瘤肿块对化疗反应迅速,由于肿块消退黄疸减轻,无需任何手术操作。作者报告了一例16岁女孩的病例,该女孩因十二指肠肿瘤导致胆道梗阻。通过内镜活检从肿块获取的标本组织学检查显示,伯基特淋巴瘤浸润十二指肠。立即开始了包括环磷酰胺在内的化疗。几天后,肿块缩小使黄疸迅速减轻。既不需要手术也不需要经皮引流。总之,非霍奇金淋巴瘤所致的胆道梗阻仅用化疗即可有效治疗,无需任何手术操作。

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