Wei Da-wen, Jia Yu-mei, Li Zhong-zheng
Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China.
Zhongguo Zhong Yao Za Zhi. 2005 Sep;30(17):1346-8.
To observe the rate of Zijin powder in inhibiting H22 mice solid and ascites liver cancer and the relation between quatity and effect.
The Kunming mics, transplanted by H22 liver cells, were divided into a model group, a cyclophosphamide group and three groups of Zijin powder in high dose, medium dose, and low dose. Then observation was made on the rate of Cancer.
The inhibiting rates of Zijin powder of three groups (high dose group, medium dose group and low dose group) for H22 mice solid liver cancer were 30.8%, 38.31% and 48.59% respectivily. The inhibiting rates of three groups of Zijin powder (low dose group, medium dose and high dose group) for H22 mice ascites liver cancer were 6.77%, 15.59% and 14.90 % respectivily.
Zijin powder has better effect on H22 mice solid liver cancer, and its effect is greatly increasing with the increased dosage.
观察紫金粉对H22小鼠实体型和腹水型肝癌的抑制率以及量效关系。
将接种H22肝癌细胞的昆明小鼠分为模型组、环磷酰胺组和紫金粉高剂量、中剂量、低剂量3组,然后观察抑瘤率。
紫金粉高、中、低剂量3组对H22小鼠实体型肝癌的抑制率分别为30.8%、38.31%、48.59%;紫金粉低、中、高剂量3组对H22小鼠腹水型肝癌的抑制率分别为6.77%、15.59%、14.90%。
紫金粉对H22小鼠实体型肝癌有较好的抑制作用,且其作用随剂量增加而明显增强。