[突尼斯中部地区急性白血病的细胞学特征]

[Cytological features of acute leukaemia in the central region of Tunisia].

作者信息

Jmili N Braham, Ben Abdelaziz A, Nagara M, Mahjoub T, Ghannem H, Kortas M

机构信息

Laboratoire d'Hématologie C.H.U. Farhat Hached, Sousse, Tunisie.

出版信息

East Mediterr Health J. 2004 Jul-Sep;10(4-5):640-7.

PMID:16335657

Abstract

In Tunisia, because of an absence of population registry, data on acute leukaemia are scarce. We studied the epidemiological and cytological characteristic of 193 patients with acute leukaemia. Haemograms were carried out and slides for peripheral blood and bone marrow were prepared for each patient. The age range of the patients was 10 months to 83 years with a predominance of males (ratio: 1.27). As regards type of leukaemia, 40.4% had acute lymphoblastic leukaemia, 51.8% had acute myeloblastic leukemia and 7.8% were unclassified. Diagnosis was made at less than 10 years in 31.6% of cases and 72% of these were the lymphoblastic type. Anaemia (Hb < 11 g/dL was found in 85% of cases, thrombocytopenia (platelets < 100 000/mm3) in 80.5% and hyperleukocytosis (WBC > 100 000/mm3) in 14.5% of cases with blasts in peripheral blood in 92% of cases.

摘要

在突尼斯，由于缺乏人口登记，急性白血病的数据很稀少。我们研究了193例急性白血病患者的流行病学和细胞学特征。对每位患者进行了血常规检查，并制备了外周血和骨髓涂片。患者的年龄范围为10个月至83岁，男性居多（比例为1.27）。关于白血病类型，40.4%为急性淋巴细胞白血病，51.8%为急性髓细胞白血病，7.8%未分类。31.6%的病例诊断时年龄小于10岁，其中72%为淋巴细胞型。85%的病例存在贫血（血红蛋白<11 g/dL），80.5%存在血小板减少（血小板<100 000/mm³），14.5%存在白细胞增多（白细胞>100 000/mm³），92%的病例外周血中有原始细胞。