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系统性的腔隙切除可降低保乳手术中的切缘阳性率和再次切除率。

Systematic cavity shaves reduces close margins and re-excision rates in breast conserving surgery.

作者信息

Janes S E J, Stankhe M, Singh S, Isgar B

机构信息

Department of General Surgery, New Cross Hospital, Wolverhampton, WV10 0QP, UK.

出版信息

Breast. 2006 Jun;15(3):326-30. doi: 10.1016/j.breast.2005.10.006. Epub 2005 Dec 5.

Abstract

The role of cavity shaves in reducing re-excision rates in breast conserving surgery (BCS) remains unclear. We compared rates of close margins and re-excision following cavity shaves based on either intraoperative radiology or systematic cavity shaves. Data was recorded prospectively from 1999 to 2003 for 217 patients undergoing BCS. For the first 106 cases, cavity shaves were performed when intraoperative radiological margins appeared close (<10 mm). The remaining 111 cases had systematic superior and inferior cavity shaves (SSICS). Close margins and re-excision rates were compared between groups. The median weight of excised tissue was less in group two: 82.8 g versus 100.5 g, P=0.001. SSICS reduced close margins by 83% (18/106 versus 8/111), OR 0.17, 95% CI 0.08-0.48, P=0.001. Multivariate analysis showed SSICS also reduced re-excision rates (15 versus 8 cases), OR 0.26, 95% CI 0.09-0.74, P=0.012. SSICS reduces close margins and re-excision rates. This approach has additional cosmetic benefits because less tissue is excised.

摘要

乳腺保乳手术(BCS)中腔面切除在降低再次切除率方面的作用仍不明确。我们比较了基于术中放射学或系统性腔面切除的腔面切除术后切缘接近和再次切除的发生率。前瞻性记录了1999年至2003年217例行BCS患者的数据。对于前106例患者,当术中放射学切缘接近(<10 mm)时进行腔面切除。其余111例患者进行系统性上下腔面切除(SSICS)。比较两组的切缘接近和再次切除率。第二组切除组织的中位数重量较少:82.8 g对100.5 g,P = 0.001。SSICS使切缘接近率降低83%(106例中的18例对111例中的8例),比值比0.17,95%可信区间0.08 - 0.48,P = 0.001。多因素分析显示SSICS也降低了再次切除率(15例对8例),比值比0.26,95%可信区间0.09 - 0.74,P = 0.012。SSICS降低了切缘接近率和再次切除率。这种方法还有额外的美容益处,因为切除的组织较少。

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