Papathanasiou K, Tolikas A, Dovas D, Kostopoulou E, Fragkedakis N, Tzafettas J
Department of Obstetrics and Gynaecology, Ippokrateio Hospital, Aristotle's University of Thessaloniki, Thessaloniki, Greece.
Int J Gynecol Cancer. 2005 Nov-Dec;15(6):1191-4. doi: 10.1111/j.1525-1438.2005.00188.x.
A case of a mucinous adenocarcinoma of the ovary with a synchronous endometroid tumor of the endometrium with focal features of undifferentiated carcinoma and deep myometrial invasion is reported. A review of the literature revealed that our case is interesting in view of the fact that simultaneous presentation of primary ovarian and endometrial neoplasms is rare and usually related to low-stage ovarian lesions and well-differentiated and superficial endometrial carcinomas in contrast to our case with the focal features of undifferentiated carcinoma and the deep myometrial invasion. These double tumors usually present in premenopausal subfertile women with abnormal uterine bleeding. The prognosis in most of the cases is surprisingly good even after total abdominal hysterectomy and bilateral oophorectomy alone without adjuvant chemotherapy or irradiation.
报告了一例卵巢黏液性腺癌,同时伴有子宫内膜样肿瘤,该肿瘤具有未分化癌的局灶性特征并侵犯子宫肌层深部。文献回顾显示,鉴于原发性卵巢和子宫内膜肿瘤同时出现的情况罕见,且通常与低分期卵巢病变以及高分化和表浅的子宫内膜癌相关,而我们的病例具有未分化癌的局灶性特征和子宫肌层深部侵犯,因此我们的病例很有意思。这些双肿瘤通常出现在有异常子宫出血的绝经前不孕妇女中。即使仅行全腹子宫切除术和双侧卵巢切除术,而不进行辅助化疗或放疗,大多数病例的预后也出奇地好。