在革兰氏阳性菌嘉西链霉菌中，氨休克导致谷氨酰胺合成酶失活。
Inactivation of Glutamine Synthetase by Ammonia Shock in the Gram-Positive Bacterium Streptomyces cattleya.
机构信息
Merck Sharp & Dohme Research Laboratories, Rahway, New Jersey 07065.
出版信息
Appl Environ Microbiol. 1982 Oct;44(4):1004-6. doi: 10.1128/aem.44.4.1004-1006.1982.
Abstract
In cultures of the gram-positive bacterium Streptomyces cattleya, a rapid inactivation of glutamine synthetase was seen after ammonia shock. pH activity curves for ammonia-shocked and control cultures are shown. A peak of glutamine synthetase activity was seen during fermentation for production of the antibiotic thienamycin.
摘要
在革兰氏阳性菌链霉菌卡特利雅的培养物中，氨冲击后谷氨酰胺合成酶迅速失活。显示了氨冲击和对照培养物的 pH 活性曲线。在生产抗生素硫霉素的发酵过程中观察到谷氨酰胺合成酶活性的峰值。
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