Ide H, Ino T, Mizuhara A, Yamaguchi A, Yamada S
Department of Cardiovascular Surgery, Jichi Medical School, Saitama, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1992 Jun;40(6):1016-20.
A 53-year-old male with a low pulmonary function (FEV1.0 500 ml) and cachexia was admitted for a remittent fever. Blood culture along with echocardiography indicating vegetation on the anterior mitral leaflet confirmed Candida endocarditis involving mitral valve. Following anti-fungal drug therapy, mitral valve replacement was performed. Surgical specimen of mitral valve showed vegetation on the anterior mitral leaflet with Candida albicans. The post-operative course was uneventful, through the anti-fungal drug therapy was compelled to be discontinued owing to drug allergy. He was discharged on the 67th postoperative day. There was no evidence of recurrence without medication for 9 months after his discharge.
一名53岁男性,肺功能低下(第一秒用力呼气容积[FEV1.0]为500毫升)且伴有恶病质,因弛张热入院。血培养以及超声心动图显示二尖瓣前叶有赘生物,确诊为累及二尖瓣的念珠菌性心内膜炎。在抗真菌药物治疗后,进行了二尖瓣置换术。二尖瓣手术标本显示二尖瓣前叶有赘生物,伴有白色念珠菌。术后过程顺利,尽管因药物过敏被迫停用抗真菌药物。他在术后第67天出院。出院后9个月未用药,无复发迹象。