小鼠生殖细胞谱系是如何建立的？
How is the mouse germ-cell lineage established?
作者信息
McLaren Anne, Lawson Kirstie A
机构信息
The Wellcome Trust/Cancer Research UK Gurdon Institute, Tennis Court Road, Cambridge CB2 1QR, UK.
出版信息
Differentiation. 2005 Dec;73(9-10):435-7. doi: 10.1111/j.1432-0436.2005.00049.x.
Abstract
Six cells have been detected in the early mouse embryo that express the transcriptional repressor Blimp1--as also do all the 40 or so cells that constitute the founder germ cell pool a day later. Are these half-dozen cells the ancestors of the entire mouse germ cell lineage?
摘要
在早期小鼠胚胎中检测到六个细胞表达转录抑制因子Blimp1，一天后构成原始生殖细胞池的约40个细胞也表达该因子。这六个细胞是整个小鼠生殖细胞谱系的祖先吗？
Zotero 插件