Slonim Noam, Atwal Gurinder Singh, Tkacik Gasper, Bialek William
Joseph Henry Laboratories of Physics, and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18297-302. doi: 10.1073/pnas.0507432102. Epub 2005 Dec 13.
In an age of increasingly large data sets, investigators in many different disciplines have turned to clustering as a tool for data analysis and exploration. Existing clustering methods, however, typically depend on several nontrivial assumptions about the structure of data. Here, we reformulate the clustering problem from an information theoretic perspective that avoids many of these assumptions. In particular, our formulation obviates the need for defining a cluster "prototype," does not require an a priori similarity metric, is invariant to changes in the representation of the data, and naturally captures nonlinear relations. We apply this approach to different domains and find that it consistently produces clusters that are more coherent than those extracted by existing algorithms. Finally, our approach provides a way of clustering based on collective notions of similarity rather than the traditional pairwise measures.
在一个数据集规模日益庞大的时代,许多不同学科的研究人员已将聚类作为一种数据分析和探索工具。然而,现有的聚类方法通常依赖于关于数据结构的若干重要假设。在此,我们从信息论角度重新构建聚类问题,从而避免了许多此类假设。具体而言,我们的公式化方法无需定义聚类“原型”,不需要先验相似性度量,对数据表示的变化具有不变性,并且能自然地捕捉非线性关系。我们将此方法应用于不同领域,发现它始终能产生比现有算法提取的聚类更连贯的聚类。最后,我们的方法提供了一种基于相似性的集体概念而非传统成对度量的聚类方式。