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过敏和哮喘中的基因表达谱分析。

Gene expression profiling in allergy and asthma.

作者信息

Schmidt-Weber Carsten B

机构信息

Swiss Institute of Allergy and Asthma Research (SIAF), Davos, Switzerland.

出版信息

Chem Immunol Allergy. 2006;91:188-94. doi: 10.1159/000090281.

Abstract

DNA array technique was applied for the simultaneous analysis of multiple genes for the characterization of diseases and for cellular analysis. This technology implicated genes in the pathogenesis of allergic disease, which were previously not discussed in this context. This article summarizes results of gene expression profiling of allergic disease and immunologically relevant cells, using DNA array technology. The results of these studies are searchable in public databases and represent exciting tools to study gene expression of diseases on a global base.

摘要

DNA阵列技术被应用于同时分析多个基因,以用于疾病特征描述和细胞分析。这项技术揭示了一些与过敏性疾病发病机制相关的基因,而这些基因此前在这一背景下未曾被讨论过。本文总结了使用DNA阵列技术对过敏性疾病和免疫相关细胞进行基因表达谱分析的结果。这些研究结果可在公共数据库中查询,并且代表了在全球范围内研究疾病基因表达的令人兴奋的工具。

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