Fokkema M R, Muskiet F A J, van Doormaal J J
Afd. Pathologie en Laboratoriumgeneeskunde, Universitair Medisch Centrum Groningen, Postbus 30.001, 9700 RB Groningen.
Ned Tijdschr Geneeskd. 2005 Nov 19;149(47):2607-12.
The high cardiovascular disease prevalence in western countries is largely attributable to the contemporary lifestyle. Interventions in the area of nutrition and physical activity have been shown to be effective in the prevention of cardiovascular disease. Successful implementation of lifestyle intervention programmes may be just as effective as drug treatment. In combination with drug treatment, intervention in the area of nutrition and physical activity is the recommended treatment for patients at a high risk of cardiovascular disease. Addition of new drugs to those presently available is associated with low absolute risk reductions and high costs, particularly in the presence of successful lifestyle interventions.
西方国家心血管疾病的高患病率很大程度上归因于当代生活方式。营养和体育活动领域的干预措施已被证明在预防心血管疾病方面是有效的。成功实施生活方式干预计划可能与药物治疗同样有效。与药物治疗相结合，营养和体育活动领域的干预是心血管疾病高危患者的推荐治疗方法。在现有药物基础上添加新药，绝对风险降低幅度小且成本高，尤其是在生活方式干预成功的情况下。
