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韩国参考成年男性模型的成对器官及其他选定吸收分数。

Paired-organ and other selected absorbed fraction for the Korean Reference Adult Male model.

作者信息

Kim J H, Whang J H, Kim C S

机构信息

Department of Nuclear Engineering College of Advanced Technology, Kyung Hee University, Korea.

出版信息

Radiat Prot Dosimetry. 2006;118(4):395-401. doi: 10.1093/rpd/nci359. Epub 2005 Dec 15.

Abstract

The authors have developed a mathematical model for calculating internal radionuclide dosimetry for the Korean Reference Adult Male, and have also derived paired-organ and other selected inter-organ photon-specific absorbed fractions for this model. Each lung, kidney and adrenal gland was set as a separate source region even though each of them shares an identical physiological function with their complementary half. The thyroid gland was also set as a source region. Specific absorbed fractions (SAFs) were then derived by selecting 10 photon energies from 0.02 to 4.0 MeV inclusive. For this purpose the Monte Carlo methodology was used, and the derived SAF was compared with the resulting value of MIRD Pamphlet No. 5 and ORNL TM-8381, both of which were derived on the basis of the ICRP-23 reference man. The comparison showed that MIRD No. 5 and ORNL TM-8381 resulted in a higher absorbed fraction, but the phantom created on the basis of the Korean reference man led to a higher SAF. The weight of the organs of the phantom, and the size and location of the trunk seem to account for the differences. The energy-dependent differences in the SAFs are considered to be related to the distance between the source and target regions, the composition of the intervening tissues, and the photon energies and mean free paths. Also, as a result of deriving SAFs after setting each separate lung, kidney and adrenal gland as a source region, it was found that, although they are of the same physiological function, each individual organ serves as a source region on its own. Differences were noted in SAFs exerted on the source and target organs in accordance with the location of the organs, that is, whether they were located to the left or right of the source organs. The SAF derived in this study can be used for a more accurate internal radionuclide dosimetry for Koreans and other Orientals whose physiology, lifestyle and dietary habits are similar to those of Koreans.

摘要

作者开发了一种用于计算韩国参考成年男性体内放射性核素剂量学的数学模型,并且还为该模型推导了成对器官以及其他选定的器官间光子特定吸收分数。即使每个肺、肾和肾上腺与其互补的另一半具有相同的生理功能,每个器官仍被设置为一个单独的源区域。甲状腺也被设置为一个源区域。然后通过从0.02至4.0 MeV(含)中选择10个光子能量来推导特定吸收分数(SAF)。为此使用了蒙特卡罗方法,并将推导得到的SAF与MIRD手册第5号和橡树岭国家实验室TM - 8381的结果值进行比较,这两者都是基于国际辐射防护委员会(ICRP)第23号参考人推导得出的。比较结果表明,MIRD第5号和橡树岭国家实验室TM - 8381得出的吸收分数更高,但基于韩国参考人创建的体模得出的SAF更高。体模器官的重量以及躯干的大小和位置似乎是造成这些差异的原因。SAF中与能量相关的差异被认为与源区域和靶区域之间的距离、中间组织的组成以及光子能量和平均自由程有关。此外,在将每个单独的肺、肾和肾上腺设置为源区域后推导SAF的结果发现,尽管它们具有相同的生理功能,但每个单独的器官自身都作为一个源区域。根据器官的位置,即在源器官的左侧还是右侧,观察到对源器官和靶器官施加的SAF存在差异。本研究中推导得到的SAF可用于为生理、生活方式和饮食习惯与韩国人相似的韩国人和其他东方人进行更准确的体内放射性核素剂量学计算。

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