Nishimoto Koshiro, Oyama Masafumi, Ando Toshiyuki, Nakajima Yosuke, Kiguchi Hideko
The Department of Urology, Saiseikai Kanagawaken Hospital.
Hinyokika Kiyo. 2005 Nov;51(11):759-61.
A 79-year-old man had undergone radical cystourethrectomy for bladder carcinoma in January, 1989. Pathological report was Small cell carcinoma (SCC) >> transitional cell carcinoma (TCC), G2 > G3, pT4 (prostate), ew (-). Ten years later, follow-up computed tomography (CT) revealed swollen left inguinal lymph node in October 1998 and lymph node dissection was performed in January, 2000. The pathological report showed TCC, G2. Left inguinal lymph node metastases appeared again in January, 2001. Chest X-ray films showed multiple lung metastases in March, 2001. Three couses of MVAC (methotrexate, vinblastine, doxorubicin cisplatinum) chemotherapy had been performed since September, 2001 but were in effective. Papillary tumor was observed at external urethral meatus in September, 2002 and the biopsied specimens showed TCC, G1 > G2, pathologically. Finally he died of respiratory insufficiency in January, 2003. It is suggested that the recurrent TCC tumor in the urethral remnants might metastasize into the inguinal lymph nodes.
一名79岁男性于1989年1月因膀胱癌接受了根治性膀胱尿道切除术。病理报告显示为小细胞癌(SCC)>>移行细胞癌(TCC),G2>G3,pT4(前列腺),ew(-)。十年后,1998年10月的随访计算机断层扫描(CT)显示左侧腹股沟淋巴结肿大,并于2000年1月进行了淋巴结清扫术。病理报告显示为TCC,G2。2001年1月左侧腹股沟淋巴结转移再次出现。2001年3月胸部X线片显示多处肺转移。自2001年9月以来进行了三个疗程的MVAC(甲氨蝶呤、长春碱、阿霉素、顺铂)化疗,但均无效。2002年9月在外尿道口观察到乳头状肿瘤,病理活检标本显示为TCC,G1>G2。最终他于2003年1月死于呼吸功能不全。提示尿道残余物中的复发性TCC肿瘤可能转移至腹股沟淋巴结。