Shimamoto Tsutomu, Iiyama Tatsuo, Karashima Takashi, Inoue Keiji, Shuin Taro, Matsumoto Manabu, Otsuki Yuji
The Department of Urology, Kochi University School of Medicine.
Hinyokika Kiyo. 2005 Nov;51(11):775-8.
Spindle cell carcinoma of the penis is extremely rare. The present case report is the nineth case in the world literature. A 71-year-old man was referred to our institution for examination of a penile tumor that showed non-specific granuloma histopathologically. We performed biopsy and total tumor resection. The histopathological finding showed squamous cell carcinoma with spindle type cells constituting the majority of the tumor, and the switching over from squamous cell carcinoma to spindle cell carcinoma was clearly visible in the histopathological examination. Therefore, we diagnosed this as spindle cell carcinoma of penis and performed partial penectomy with inguinal lymph node dissection. Spindle cell carcinoma is an uncommon variant of squamous cell carcinoma. We report the histopathological findings including the data of p53 immunohistochemical study, and reviewed the eight previous reports of spindle cell carcinoma of the penis.
阴茎梭形细胞癌极为罕见。本病例报告是世界文献中的第九例。一名71岁男性因阴茎肿瘤前来我院检查,该肿瘤组织病理学显示为非特异性肉芽肿。我们进行了活检和肿瘤全切术。组织病理学检查发现为鳞状细胞癌,其中梭形细胞占肿瘤的大部分,且在组织病理学检查中可见从鳞状细胞癌向梭形细胞癌的转变。因此,我们将其诊断为阴茎梭形细胞癌,并进行了阴茎部分切除术及腹股沟淋巴结清扫术。梭形细胞癌是鳞状细胞癌的一种罕见变异型。我们报告了组织病理学检查结果,包括p53免疫组化研究数据,并回顾了此前关于阴茎梭形细胞癌的八篇报告。