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双侧腹腔镜根治性肾切除术治疗获得性囊性肾病患者的肾肿瘤

Bilateral laparoscopic radical nephrectomy for renal tumors in patients with acquired cystic kidney disease.

作者信息

Ghasemian S Reza, Pedraza Roberto, Sasaki Truman A, Light Jimmy A, Patel Sunil V

机构信息

Department of Urology, Washington Hospital Center, Washington, DC 20010, USA.

出版信息

J Laparoendosc Adv Surg Tech A. 2005 Dec;15(6):606-10. doi: 10.1089/lap.2005.15.606.

Abstract

PURPOSE

We describe our experience with simultaneous bilateral laparoscopic radical nephrectomy performed in patients with acquired cystic kidney disease (ACKD) and renal tumors.

MATERIALS AND METHODS

Between June 2000 and September 2002, 10 patients with ACKD underwent simultaneous bilateral laparoscopic radical nephrectomy for renal lesions suspicious for carcinoma. The lesions were discovered during pretransplant evaluation in 9 patients and incidentally in 1 renal transplant recipient. A 3- or 4-port transperitoneal approach was used for each side to mobilize the kidney and secure the renal hilum. Both specimens were extracted through a midline supraumbilical incision. Operative time, blood loss, analgesic requirements, hospital stay, and convalescence and recurrence rates were determined.

RESULTS

The mean age of the patients was 41.6 years (range, 29-47 years). Mean operative time was 6.5 hours (range, 4.5-9.7 hours) and mean estimated blood loss was 164 cc (range, 50-300 cc). There was one intraoperative complication-a clotted arteriovenous (AV) graft; and 2 postoperative complications-1 fluid overload and 1 adrenal insufficiency. The average length of hospital stay was 3.1 days (range, 2-4 days) and mean convalescence was 2.8 weeks (range, 1-6 weeks). All cancers were confined to the kidneys and there has been no recurrence during follow-up ranging from 6 to 26 months.

CONCLUSION

Bilateral laparoscopic radical nephrectomy in end-stage renal disease patients is safe and feasible. The advantages of the laparoscopic approach include minimal intraoperative blood loss, shorter hospital stay, minimal postoperative pain, and a rapid return to normal activity. The laparoscopic technique offers an effective, minimally invasive therapeutic alternative to open surgery in high-risk end-stage renal disease patients.

摘要

目的

我们描述了在患有获得性囊性肾病(ACKD)和肾肿瘤的患者中进行同期双侧腹腔镜根治性肾切除术的经验。

材料与方法

2000年6月至2002年9月期间,10例患有ACKD的患者因怀疑有癌的肾脏病变接受了同期双侧腹腔镜根治性肾切除术。9例患者在移植前评估期间发现病变,1例肾移植受者为偶然发现。每侧采用三孔或四孔经腹途径游离肾脏并处理肾蒂。两个标本均通过脐上正中切口取出。确定手术时间、失血量、镇痛需求、住院时间、康复情况及复发率。

结果

患者的平均年龄为41.6岁(范围29 - 47岁)。平均手术时间为6.5小时(范围4.5 - 9.7小时),平均估计失血量为164毫升(范围50 - 300毫升)。有1例术中并发症——动静脉(AV)移植物血栓形成;2例术后并发症——1例液体超负荷和1例肾上腺功能不全。平均住院时间为3.1天(范围2 - 4天),平均康复时间为2.8周(范围1 - 6周)。所有癌症均局限于肾脏,在6至26个月的随访期间无复发。

结论

终末期肾病患者的双侧腹腔镜根治性肾切除术是安全可行的。腹腔镜手术方法的优点包括术中失血极少、住院时间短、术后疼痛轻微以及能迅速恢复正常活动。腹腔镜技术为高危终末期肾病患者提供了一种有效的、微创的替代开放手术的治疗方法。

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