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[早期浸润性膀胱癌的治疗困境]

[The therapeutic dilemma of the early invasive bladder cancer].

作者信息

Caviezel Alessandro, Pelte Marie-Françoise, Fateri Farchid, Iselin Christophe

机构信息

Service d'urologie, Département de chirurgie, HUG, 1211 Genève 14.

出版信息

Rev Med Suisse. 2005 Dec 7;1(44):2849-50, 2853.

Abstract

Transitional tumours of the bladder are classically divided in superficial (lesions of the mucosa and the submucosa) and invasive (infiltrating the detrusor) cancers. However, the recurrence and progression rate of submucosal urothelial cancers is highly variable. Therefore, management of such neoplasias is very challenging, some patients requiring a cystectomy, whereas others can be managed less invasively with endoscopic resection eventually associated with intravesical chemotherapy. We review herein the prognostic factors which help us to orientate our patients. We also emphasize the importance of the subclassification of the micro-invasive stage, and its practicability, which is reliable and simple, as opposed to the general belief.

摘要

膀胱移行性肿瘤传统上分为表浅性(黏膜和黏膜下层病变)和浸润性(浸润逼尿肌)癌。然而,黏膜下层尿路上皮癌的复发率和进展率差异很大。因此,这类肿瘤的治疗极具挑战性,一些患者需要进行膀胱切除术,而另一些患者最终可通过内镜切除并联合膀胱内化疗进行微创治疗。我们在此回顾有助于指导患者治疗的预后因素。我们还强调了微浸润期亚分类的重要性及其实用性,与普遍看法相反,这种分类可靠且简单。

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