Minichini C, Sciarrino A
Dipartimento di Scienze Fisiche, Università di Napoli "Federico II", I-80126 Naples, Italy.
Biosystems. 2006 Jun;84(3):191-206. doi: 10.1016/j.biosystems.2005.11.003. Epub 2006 Jan 4.
A nucleotide sequence is identified, using a two (four)-letter alphabet, by the the labels of a vector state of an irreducible representation of Uq-->0(sl(2)) (Uq-->0(sl(2) plus sign in circle sl(2))). A master equation for the distribution function is written, where the intensity of the one-spin flip is assumed to depend on the variation of the labels of the state. In the two-letter approximation, the numerically computed equilibrium distribution for short sequences is fitted nicely by a Yule distribution, which is the observed distribution of the ranked short oligonucleotides frequency in DNA. The four-letter alphabet description, applied to the codons, is able to reproduce the form of the fitted rank-ordered usage frequencies distribution.
使用双(四)字母表,通过Uq→0(sl(2))(Uq→0(sl(2) 加圆圈sl(2)))不可约表示的矢量态标签来识别核苷酸序列。写出了分布函数的主方程,其中假设单自旋翻转强度取决于态标签的变化。在双字母近似中,短序列的数值计算平衡分布能很好地由尤尔分布拟合,尤尔分布是DNA中排序后的短寡核苷酸频率的观测分布。应用于密码子的四字母表描述能够重现拟合的排序使用频率分布的形式。