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巩膜外扩展与睫状体脉络膜黑色素瘤的关系:超声生物显微镜检查及其组织病理学相关性

Extrascleral extension in association with ciliochoroidal melanoma: ultrasound biomicroscopy with histopathological correlation.

作者信息

Noble Jason, Qazi Faqir A, Lakosha Hesham K, Simpson E Rand, Yucel Yeni, McGowan Hugh, Pavlin Charles, Altomare Filiberto

机构信息

The Department of Ocular Oncology, Princess Margaret Hospital, University health Network, Toronto, Ont.

出版信息

Can J Ophthalmol. 2005 Oct;40(5):616-8. doi: 10.1016/S0008-4182(05)80056-0.

Abstract

CASE REPORT

We present the case of a 71-year-old man with a melanoma arising from the ciliary body and extending into the choroid. Ultrasound biomicroscopy (UBM) revealed connection via an emissary canal to a subconjunctival nodule. Although evaluation for metastasis was negative at the time of diagnosis, multiple hepatic metastatic deposits were found 2 years post-enucleation.

COMMENTS

It is crucial to identify the presence of scleral invasion and extrascleral extension for proper management planning in patients with choroidal melanomas. This case demonstrates that UBM is an accurate and useful tool for characterizing the morphologic pattern of scleral invasion of intraocular tumours.

摘要

病例报告

我们报告一例71岁男性患者,其黑色素瘤起源于睫状体并延伸至脉络膜。超声生物显微镜检查(UBM)显示通过一条导血管与结膜下结节相连。尽管诊断时转移评估为阴性,但眼球摘除术后2年发现多处肝脏转移灶。

评论

对于脉络膜黑色素瘤患者,确定巩膜侵犯和巩膜外扩展的存在对于制定恰当的治疗计划至关重要。该病例表明,UBM是一种准确且有用的工具,可用于描述眼内肿瘤巩膜侵犯的形态学模式。

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