Mukhopadhyay Amiya Kumar
Indian J Dermatol Venereol Leprol. 2005 Nov-Dec;71(6):421-2. doi: 10.4103/0378-6323.18949.
Blaschko's lines form a pattern, which many diseases are found to follow, but linear scleroderma following Blaschko's lines is a controversial entity rarely reported in the literature. A 24-year-old man presented with multiple linear, atrophic, hyperpigmented lesions punctuated by areas of depigmentations on the left half of the trunk distributed on the anterior, lateral and posterior aspects. The lesions were distributed in a typical S-shaped line. Antinuclear antibody and antihistone antibody tests were negative. Histopathological examination of the skin from the affected area showed features suggestive of scleroderma. Here, we present a case of linear scleroderma following Blaschko's lines in a male patient--an entity reported only three times so far.
布拉斯科线形成一种模式,许多疾病被发现遵循这种模式,但沿布拉斯科线分布的线状硬皮病是一个有争议的实体,在文献中很少报道。一名24岁男性患者,躯干左侧前、侧、后部分出现多个线性、萎缩性、色素沉着过度的皮损,其间有色素脱失区域。皮损呈典型的S形分布。抗核抗体和抗组蛋白抗体检测均为阴性。对受累部位皮肤的组织病理学检查显示有硬皮病的特征。在此,我们报告一例男性患者沿布拉斯科线分布的线状硬皮病——该实体迄今为止仅被报道过三次。