Paré Emmanuelle, Quiñones Joanne N, Macones George A
Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
BJOG. 2006 Jan;113(1):75-85. doi: 10.1111/j.1471-0528.2005.00793.x.
To compare the maternal implications of strategies of vaginal birth after caesarean section (VBAC) attempt versus elective repeat caesarean section in women with one previous lower segment caesarean section.
Decision model.
Women with one prior low transverse caesarean section who are eligible for trial of labour.
Two decision models were built: the first one applying to women planning only one more pregnancy, the second one applying to women planning two more pregnancies. Probability estimates for VBAC success rate and risks of uterine rupture, placenta praevia, placenta accreta and hysterectomy were extracted from the available literature.
Hysterectomy for uterine rupture, placenta accreta or other indications.
In the first model VBAC attempt led to a higher hysterectomy rate (267/100,000) compared with repeat caesarean section (187/100,000). However, in the second model a policy of elective repeat caesarean section led to higher cumulative hysterectomy rate: 1465/100,000 versus 907/100,000 for VBAC. The first model was robust to all but one variable in sensitivity analyses. The second model was robust to all variables in sensitivity analyses.
These results indicate that long term reproductive consequences of multiple caesarean sections should be considered when making policy decisions regarding the risk-benefit ratio of VBAC.
比较有过一次下段剖宫产史的女性尝试剖宫产术后阴道分娩(VBAC)策略与择期再次剖宫产对母亲的影响。
决策模型。
有过一次低位横切口剖宫产史且适合试产的女性。
构建了两个决策模型:第一个适用于仅计划再怀孕一次的女性,第二个适用于计划再怀孕两次的女性。从现有文献中提取VBAC成功率以及子宫破裂、前置胎盘、胎盘植入和子宫切除风险的概率估计值。
因子宫破裂、胎盘植入或其他指征行子宫切除术。
在第一个模型中,与再次剖宫产(187/10万)相比,尝试VBAC导致更高的子宫切除率(267/10万)。然而,在第二个模型中,择期再次剖宫产策略导致更高的累积子宫切除率:VBAC为907/10万,择期再次剖宫产为1465/10万。在敏感性分析中,第一个模型对除一个变量外的所有变量均具有稳健性。第二个模型对敏感性分析中的所有变量均具有稳健性。
这些结果表明,在就VBAC的风险效益比做出决策时,应考虑多次剖宫产的长期生殖后果。