Das Satyajit
Department of GU & HIV Medicine, University Hospitals Coventry & Warwickshire, Stoney Stanton Road, Coventry, UK.
Sex Health. 2005;2(4):219-21. doi: 10.1071/sh05033.
Highly active antiretroviral therapy (HAART) has significantly increased the survival rate of patients with HIV. However, abnormalities of lipid and insulin metabolism have been recognised and there is an increasing prevalence of fat redistribution, frank diabetes and hyperlipidaemia in HIV-infected patients receiving HAART. Several observational studies have described associations between HIV infection, HAART and cardiovascular disease. The management of risk factors for cardiovascular disease is expected to play an important role in the treatment of HIV infection.
高效抗逆转录病毒疗法(HAART)显著提高了HIV患者的生存率。然而,脂质和胰岛素代谢异常已被认识到,并且在接受HAART的HIV感染患者中,脂肪重新分布、显性糖尿病和高脂血症的患病率正在上升。几项观察性研究描述了HIV感染、HAART与心血管疾病之间的关联。心血管疾病危险因素的管理有望在HIV感染的治疗中发挥重要作用。