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肝胆恶性肿瘤的术前门静脉栓塞:朱拉隆功国王纪念医院的经验

Preoperative portal vein embolization in hepatobiliary tract malignancy: an experience at King Chulalongkorn Memorial Hospital.

作者信息

Sirichindakul Boonchoo, Nonthasoot Bunthoon, Thienpaitoon Peera, Nivatvongs Supanit, Janchai Akkawat

机构信息

Department of Surgery, King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand.

出版信息

J Med Assoc Thai. 2005 Aug;88(8):1115-9.

Abstract

BACKGROUND

Major hepatic resections are increasingly performed for both primary and secondary liver cancers nowadays. However, morbidity from these operations is still high. One of the dreadful complications, sometimes lead to fatality, is postoperative liver failure. There are many factors which are associated with this complication such as chronic liver disease, low residual liver volume after resection. Portal vein embolization (PVE) is the procedure which increases the liver volume of the non-embolized lobe. Now, PVE has gained acceptance in many centers to overcome or reduce this complication. This report described the authors' experiences of PVE since 2001 at King Chulalongkorn Memorial Hospital.

MATERIAL AND METHOD

The records of 10 patients who had PVE were reviewed CT volumetry of the liver was done before and after procedure. The authors calculated future liver remnant from CT volumetry and compared this volume to standard liver volume. The postoperative complications and hospital courses of these patients were also recorded.

RESULTS

Mean growth of future liver remnant (FLR) ratio after PVE was 13.7 +/- 6.2% (median 13, range 4-25). There was no major complication after PVE. Six patients underwent liver resection and there was no major complication or mortality. No one had persistent hyperbilirubinemia 2 weeks after operation.

CONCLUSION

The PVE is the useful and safe optional procedure to increase future liver remnant volume. It not only reduces the postoperative liver failure but increases the chance for curative resection.

摘要

背景

如今,原发性和继发性肝癌的大型肝切除术越来越多。然而,这些手术的发病率仍然很高。术后肝衰竭是一种可怕的并发症,有时会导致死亡。有许多因素与这种并发症相关,如慢性肝病、切除后残余肝体积小。门静脉栓塞术(PVE)是一种增加未栓塞肝叶体积的手术。现在,PVE已在许多中心得到认可,以克服或减少这种并发症。本报告描述了作者自2001年以来在朱拉隆功国王纪念医院进行PVE的经验。

材料与方法

回顾了10例行PVE患者的记录,在手术前后进行肝脏CT容积测量。作者通过CT容积测量计算未来肝残余量,并将该体积与标准肝体积进行比较。还记录了这些患者的术后并发症和住院过程。

结果

PVE后未来肝残余(FLR)比率的平均增长为13.7±6.2%(中位数13,范围4-25)。PVE后无重大并发症。6例患者接受了肝切除术,无重大并发症或死亡。术后2周无人出现持续性高胆红素血症。

结论

PVE是增加未来肝残余体积的一种有用且安全的选择手术。它不仅减少了术后肝衰竭,还增加了根治性切除的机会。

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