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胎儿磁共振成像与人类遗传学。

Fetal magnetic resonance imaging and human genetics.

作者信息

Hengstschläger Markus

机构信息

Medical Genetics, Obstetrics and Gynecology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

出版信息

Eur J Radiol. 2006 Feb;57(2):312-5. doi: 10.1016/j.ejrad.2005.11.029. Epub 2006 Jan 6.

Abstract

The use of fetal magnetic resonance imaging (MRI), in addition to prenatal genetic testing and sonography, has the potential to improve prenatal diagnosis of genetic disorders. MRI plays an important role in the evaluation of fetal abnormalities and malformations. Fetal MRI often enables a differential diagnosis, a determination of the extent of the disorder, the prognosis, and an improvement in therapeutic management. For counseling of parents, as well as to basically understand how genetic aberrations affect fetal development, it is of great importance to correlate different genotypes with fetal MRI data.

摘要

除了产前基因检测和超声检查外,使用胎儿磁共振成像(MRI)有改善遗传性疾病产前诊断的潜力。MRI在评估胎儿异常和畸形方面发挥着重要作用。胎儿MRI常常能够实现鉴别诊断、确定疾病范围、判断预后,并改善治疗管理。为了给父母提供咨询,以及从根本上了解基因畸变如何影响胎儿发育,将不同的基因型与胎儿MRI数据相关联非常重要。

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