Patel Nick C, Delbello Melissa P, Strakowski Stephen M
The College of Pharmacy, University of Cincinnati, OH 45267-0004, USA.
Bipolar Disord. 2006 Feb;8(1):95-9. doi: 10.1111/j.1399-5618.2006.00279.x.
To compare symptom profiles of African-American and white adolescents with a diagnosis of bipolar disorder.
Adolescents, aged 12-18 years at their first psychiatric hospitalization, with a DSM-IV diagnosis of bipolar disorder, manic or mixed, were evaluated on measures of manic, depressive, and positive symptoms of psychosis. Ethnic differences in symptom profiles were examined using multivariate analysis of covariance, and specific symptoms contributing to the difference were analyzed.
Ethnic differences existed in manic and positive symptom profiles, but not depressive symptoms. Compared with the white cohort, African-American youths were diagnosed more frequently as having psychotic features, and had higher ratings for auditory hallucinations.
Similar to adults, symptom expression in adolescent bipolar disorder may differ between ethnic groups. Future studies are needed to replicate these findings and explore possible explanations.
比较被诊断为双相情感障碍的非裔美国青少年和白人青少年的症状特征。
对首次因精神疾病住院、年龄在12至18岁、根据《精神疾病诊断与统计手册第四版》(DSM-IV)被诊断为双相情感障碍(躁狂或混合发作)的青少年,进行躁狂、抑郁和精神病性阳性症状的评估。使用多变量协方差分析检查症状特征的种族差异,并分析导致差异的具体症状。
在躁狂和阳性症状特征方面存在种族差异,但在抑郁症状方面不存在。与白人队列相比,非裔美国青少年被诊断为有精神病性特征的频率更高,且幻听评分更高。
与成年人相似,青少年双相情感障碍的症状表现可能因种族而异。需要进一步研究来重复这些发现并探索可能的解释。