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可吸收接骨板系统中的延迟降解

Delayed degradation in a resorbable plating system.

作者信息

Mackool Richard, Yim Jun, McCarthy Joseph G

机构信息

Institute of Reconstructive Plastic Surgery, New York University Medical Center, New York, NY, USA.

出版信息

J Craniofac Surg. 2006 Jan;17(1):194-7; discussion 197-8. doi: 10.1097/01.scs.0000194167.50546.7e.

Abstract

Resorbable plating systems are used extensively for craniofacial reconstruction, particularly in children. The systems provide rigid fixation while potentially minimizing the long-term drawbacks of permanent plating systems such as plate "migration," bone growth restriction, and imaging artifact. However, the need for active plate resorption represents both the strength and weakness of these fixation systems. We present four patients who underwent cranial vault remodeling using a resorbable plating system, following which the plates were palpable and observable for at least 2 years postoperatively. All required surgical removal. On gross inspection, the plates had been replaced by an encapsulated spongy material containing yellow, grainy, cloudy liquid. The bone underlying the plates was depressed and irregular in contour when compared with the adjacent bone. Microscopic studies showed a giant cell foreign-body reaction with crystalline material present in the cell vacuoles.

摘要

可吸收接骨板系统广泛应用于颅面重建,尤其是在儿童患者中。该系统可提供牢固的固定,同时可能将永久性接骨板系统的长期缺点(如接骨板“移位”、骨生长受限和成像伪影)降至最低。然而,接骨板的主动吸收需求既体现了这些固定系统的优势,也暴露了其劣势。我们报告了4例使用可吸收接骨板系统进行颅盖重塑的患者,术后至少2年内可触及并观察到接骨板,所有患者均需手术取出。大体检查显示,接骨板已被一种包裹性海绵状物质取代,该物质含有黄色、颗粒状、浑浊液体。与相邻骨相比,接骨板下方的骨凹陷且轮廓不规则。显微镜研究显示存在巨细胞异物反应,细胞空泡内有结晶物质。

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