Weigang Ernst, Hartert Marc, Siegenthaler Michael P, Pitzer-Hartert Katrin, Luehr Maximilian, Sircar Ronen, von Samson Patrick, Beyersdorf Friedhelm
Department of Cardiovascular Surgery, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany.
Eur J Cardiothorac Surg. 2006 Mar;29(3):392-6. doi: 10.1016/j.ejcts.2005.11.039. Epub 2006 Jan 24.
The aim of this study was to evaluate the benefit of neurophysiological monitoring during thoracic and thoracoabdominal endovascular stent graft implantation.
The spinal cords of 21 patients undergoing endovascular stent graft implantation on the thoracic and thoracoabdominal aorta were monitored with transcranial motor-evoked potentials (tcMEP) and somatosensory-evoked potentials (SSEP). All patients underwent mild systemic hypothermia (34-35 degrees C), constant cerebrospinal fluid (CSF) pressure and vital parameter monitoring. If CSF pressure exceeded 15 mmHg, CSF-drainage was carried out.
Three of the 21 patients (14%) exhibited short-term loss of tcMEP and SSEP after the deployment of the self-expanding endoprosthesis. We observed an intraoperative recovery of the evoked potentials in all cases. CSF-drainage was necessary in three of them. One patient, whose potentials were stable intraoperatively, developed paraparesis 3 weeks after the intervention.
Neurophysiological monitoring has proved to be an ideal monitoring method to detect spinal cord ischemia during thoracic and thoracoabdominal endovascular stent graft implantation. Due to the advantages of endovascular therapy (no aortic cross-clamping, continuous distal perfusion, and no reperfusion injury), changes in potentials were seldom observed.
本研究旨在评估胸段和胸腹段血管内支架植入术中神经生理监测的益处。
对21例接受胸段和胸腹段主动脉血管内支架植入术的患者,采用经颅运动诱发电位(tcMEP)和体感诱发电位(SSEP)监测脊髓功能。所有患者均接受轻度全身低温(34 - 35摄氏度)、持续脑脊液(CSF)压力及生命参数监测。若脑脊液压力超过15 mmHg,则进行脑脊液引流。
21例患者中有3例(14%)在自膨式血管内假体释放后出现tcMEP和SSEP短期消失。所有病例中我们均观察到诱发电位在术中恢复。其中3例需要进行脑脊液引流。1例患者术中电位稳定,但在干预后3周出现双下肢轻瘫。
神经生理监测已被证明是检测胸段和胸腹段血管内支架植入术中脊髓缺血的理想监测方法。由于血管内治疗的优势(无需主动脉阻断、持续远端灌注且无再灌注损伤),很少观察到电位变化。