Topilski Ian, Glick Aharon, Viskin Sami, Belhassen Bernard
Department of Cardiology, Tel-Aviv Sourasky Medical Center, and the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Pacing Clin Electrophysiol. 2006 Jan;29(1):21-8. doi: 10.1111/j.1540-8159.2006.00293.x.
We sought to assess the frequency of spontaneous or inducible atrioventricular nodal reentry tachycardia (AVNRT) in patients referred for radiofrequency ablation (RFA) of idiopathic outflow tract ventricular arrhythmias.
In patients with no obvious heart disease, AVNRT and outflow tract ventricular tachycardia (VT) are the most frequently encountered supraventricular and ventricular tachycardias, respectively. An increased coexistence of the two arrhythmias has been recently suggested.
In 68 consecutive patients referred for RFA of an idiopathic ventricular outflow tract arrhythmia, a stimulation protocol including repeated bursts of rapid atrial pacing, up to triple atrial extrastimuli during sinus rhythm and rapid ventricular pacing was performed before and after isoproterenol infusion following RFA of the ventricular arrhythmia. In patients with inducible AVNRT, RFA of the slow pathway was performed.
Of the 68 study patients, 17 (25%) had either spontaneous AVNRT documented prior to RFA of the ventricular arrhythmia (n = 4) or inducible AVNRT at the time of RFA of the ventricular arrhythmia (n = 13). AVNRT was induced by atrial pacing in 15 (88%) of 17 patients: in 3 patients without isoproterenol and in 12 patients during isoproterenol infusion. Uncomplicated RFA of the slow pathway was successfully achieved in all patients with inducible AVNRT.
Spontaneous or inducible AVNRT is relatively common in patients with idiopathic outflow tract ventricular arrhythmias. Atrial stimulation, especially when performed after isoproterenol infusion plays a major role in AVNRT inducibility. Although we performed RFA of the slow pathway in patients with inducible AVNRT and no prior tachycardia documentation, the question whether this is mandatory remains unsettled.
我们试图评估因特发性流出道室性心律失常接受射频消融(RFA)治疗的患者中,自发或可诱发的房室结折返性心动过速(AVNRT)的发生率。
在无明显心脏病的患者中,AVNRT和流出道室性心动过速(VT)分别是最常见的室上性和室性心动过速。最近有研究表明这两种心律失常共存的情况有所增加。
在68例因特发性室性流出道心律失常接受RFA治疗的连续患者中,在室性心律失常RFA后异丙肾上腺素输注前后,进行了包括重复快速心房起搏、窦性心律时最多三联心房额外刺激以及快速心室起搏的刺激方案。对于可诱发AVNRT的患者,进行慢径路RFA。
在68例研究患者中,17例(25%)在室性心律失常RFA之前记录到有自发AVNRT(n = 4),或在室性心律失常RFA时可诱发AVNRT(n = 13)。17例患者中有15例(88%)通过心房起搏诱发了AVNRT:3例在未使用异丙肾上腺素时诱发,12例在异丙肾上腺素输注期间诱发。所有可诱发AVNRT的患者均成功完成了无并发症的慢径路RFA。
自发或可诱发的AVNRT在特发性流出道室性心律失常患者中相对常见。心房刺激,尤其是在异丙肾上腺素输注后进行的刺激,在AVNRT的诱发中起主要作用。尽管我们对可诱发AVNRT且既往无心动过速记录的患者进行了慢径路RFA,但这是否为必需操作的问题仍未解决。