Kadzhaia D, Merabishvili N
Tbilisi State Medical University; Obstetric Clinic N2, Tbilisi, Georgia.
Georgian Med News. 2005 Dec(129):33-6.
The aim of this study was to determine the prevalence and risk factors for Chlamydia trachomatis infection in pregnant women. A total of 351 asymptomatic pregnant women (first to second trimesters; age range: 15-30 years) were examined. The background data related to social and marital status, age, anamnestic data were also recorded. Serum samples were tested for IgM antibodies specific to Chlamydia trachomatis by an enzyme-linked immunosorbent assay (ELISA). In the present study the overall rate of C trachomatis infections in pregnant women was 33% including 41 women (38.7%) under 20 years, 39 women (36.8%) in age of 21-25, and 26 women (24.5%) in age of 25-30. The age group under 20 years exhibited higher risk of infection. There was a significant correlation between the Chlamydia trachomatis infection rate and clinical risk factors such as rare visits to the gynecologist, pelvic inflammatory disease, premature delivery, spontaneous abortions, ectopic pregnancies, C. trachomatis-positivity, chlamydial cervicitis in anamnesis. The prevalence of asymptomatic C. trachomatis infection in pregnant women is 72.6%, therefore, we suggest the screening for chlamydial infection of all pregnant women at least once during their pregnancy.
本研究的目的是确定孕妇沙眼衣原体感染的患病率及危险因素。共检查了351名无症状孕妇(孕早期至孕中期;年龄范围:15 - 30岁)。还记录了与社会和婚姻状况、年龄、既往史相关的背景数据。通过酶联免疫吸附测定(ELISA)检测血清样本中沙眼衣原体特异性IgM抗体。在本研究中,孕妇沙眼衣原体感染的总体发生率为33%,其中20岁以下的有41名女性(38.7%),21 - 25岁的有39名女性(36.8%),25 - 30岁的有26名女性(24.5%)。20岁以下年龄组感染风险较高。沙眼衣原体感染率与临床危险因素之间存在显著相关性,如很少看妇科医生、盆腔炎、早产、自然流产、宫外孕、沙眼衣原体阳性、既往衣原体宫颈炎。孕妇无症状沙眼衣原体感染的患病率为72.6%,因此,我们建议对所有孕妇在孕期至少进行一次衣原体感染筛查。