Taboada Giselle F, van Haute Flávia R, Corrêa Lívia L, Casini Alessandra F, Gadelha Mônica R
Endocrine Unit, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ.
Arq Bras Endocrinol Metabol. 2005 Oct;49(5):626-40. doi: 10.1590/s0004-27302005000500004. Epub 2006 Jan 23.
Acromegaly is a systemic disease with various etiologies. It can occur as a sporadic or, more rarely, as a familial disease. Numerous complications such as endocrine, cardiovascular, respiratory, metabolic, osteoarticular and neoplastic disturbances occur and must be taken into account when establishing a therapeutic strategy. For this reason, the decision as to a treatment modality of acromegaly must be followed by a thorough evaluation of the patient and once the diagnosis of complications is settled, adequate treatment should be instituted. Follow up of the patients requires periodical re-assessment of complications status.
肢端肥大症是一种病因多样的全身性疾病。它可散发出现,或更罕见地,作为一种家族性疾病出现。会发生许多并发症,如内分泌、心血管、呼吸、代谢、骨关节和肿瘤紊乱,在制定治疗策略时必须予以考虑。因此,在决定肢端肥大症的治疗方式后,必须对患者进行全面评估,一旦确定并发症的诊断,就应进行适当治疗。对患者的随访需要定期重新评估并发症状况。