Siqueira S R D T, Nóbrega J C M, Teixeira M J, Siqueira J T T
Dentistry Division, Hospital das Clínicas, Medical School, University of São Paulo, SP, Brazil.
Clin Neurol Neurosurg. 2006 Dec;108(8):721-5. doi: 10.1016/j.clineuro.2005.12.007. Epub 2006 Jan 30.
Idiopathic trigeminal neuralgia (ITN) is a well-known disease often treated with neurosurgical procedures, which may produce sensorial abnormalities, such as numbness, dysesthesia and taste complaints. We studied 12 patients that underwent this technique, in order to verify pain, gustative and olfactory thresholds abnormalities, with a follow-up of 120 days. We compared the patients with a matched control group of 12 patients. Our results found a significant difference in the olfactory threshold at the immediate post-operative period (p=0.048). We concluded that injured trigeminal fibers are probably associated with the increase in the olfactory threshold after the surgery, supporting the sensorial interaction theory.
特发性三叉神经痛（ITN）是一种常见疾病，常采用神经外科手术治疗，这种手术可能会导致感觉异常，如麻木、感觉迟钝和味觉异常。我们研究了12例接受该手术的患者，以验证疼痛、味觉和嗅觉阈值异常情况，并进行了120天的随访。我们将这些患者与12例相匹配的对照组患者进行了比较。我们的结果发现，术后即刻嗅觉阈值存在显著差异（p = 0.048）。我们得出结论，受损的三叉神经纤维可能与术后嗅觉阈值升高有关，这支持了感觉相互作用理论。
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