莱文廷病的光学相干断层扫描特征
Optical coherent tomography features of malattia leventinese.
作者信息
Souied Eric H, Leveziel Nicolas, Letien Valerie, Darmon Jacques, Coscas Gabriel, Soubrane Gisele
机构信息
Clinique Ophthamologique Universitaire de Créteil, Höpital Intercommunal, Créteil, France.
出版信息
Am J Ophthalmol. 2006 Feb;141(2):404-7. doi: 10.1016/j.ajo.2005.09.001.
PURPOSE
Malattia leventinese (ML) is an inherited macular degeneration characterized by the presence of large paracentral and small radial drusen. Our purpose was to describe optical coherent tomography (OCT) features observed in ML.
DESIGN
Prospective observational case series.
METHODS
Ten eyes from five patients with ML aged 27 to 44 years were prospectively included. Best-corrected visual acuity, fundus color photography of the retina, and OCT were performed in each patient.
RESULTS
OCT revealed a hyperreflective thickening of the retinal pigment epithelium-Bruch membrane complex, associated with localized dome-shaped elevations. Retinal thickness above the drusen ranged from 221 to 292 microm (mean 260 microm). Foveal thickness ranged from 72 to 200 microm (mean 144 microm)
CONCLUSIONS
The large paracentral drusen presented either as a thickening of the retinal pigment epithelium-Bruch complex or as local limited elevation of retinal pigment epithelium-Bruch complex, both associated with preservation of the neurosensory retina.
目的
莱文廷斯病（ML）是一种遗传性黄斑变性，其特征为存在大的中心旁和小的放射状玻璃膜疣。我们的目的是描述在ML中观察到的光学相干断层扫描（OCT）特征。
设计
前瞻性观察病例系列。
方法
前瞻性纳入了5例年龄在27至44岁之间的ML患者的10只眼睛。对每位患者进行最佳矫正视力、视网膜眼底彩色照相和OCT检查。
结果
OCT显示视网膜色素上皮-布鲁赫膜复合体的高反射性增厚，并伴有局部圆顶状隆起。玻璃膜疣上方的视网膜厚度为221至292微米（平均260微米）。黄斑中心凹厚度为72至200微米（平均144微米）。
结论
大的中心旁玻璃膜疣表现为视网膜色素上皮-布鲁赫复合体增厚或视网膜色素上皮-布鲁赫复合体局部局限性隆起，两者均与神经感觉视网膜的保存有关。
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