Merseburger A S, Hennenlotter J, Schilling D, Sievert K D, Küfer R, Kuczyk M A
Abteilung für Urologie, Eberhard Karls-Universität, Tübingen.
Urologe A. 2006 Mar;45(3):323-4, 326-7. doi: 10.1007/s00120-006-1005-y.
The tissue microarray technique (TMA) represents a powerful diagnostic "high-throughput" tool to analyse DNA/RNA or protein alterations in large patient cohorts in a time and cost effective way. This review focuses on the clinical application of TMA in renal cell carcinoma in modern "translational" medicine--"from bench to bedside". In particular, the advantages of TMA for diagnosis, prognosis and decisions for therapy will be considered in relation to renal cell cancer.
组织微阵列技术(TMA)是一种强大的诊断“高通量”工具,能够以经济高效的方式分析大量患者队列中的DNA/RNA或蛋白质改变。本综述聚焦于TMA在现代“转化”医学——“从实验室到临床”中在肾细胞癌方面的临床应用。特别是,将结合肾细胞癌来探讨TMA在诊断、预后及治疗决策方面的优势。