Bronzino P, Abbo L, Bagnasco F, Barisone P, Dezzani C, Genovese A M, Iannucci P, Ippoliti M, Sacchi M, Aimo I
Struttura Complessa Chirurgia Generale, Ospedale Santa Croce, Mondovì.
G Chir. 2005 Nov-Dec;26(11-12):419-21.
Splenic marginal zone lymphomas are rare tumors which take origin from the B cells. More common in the elderly, often asymptomatic, they can present with abdominal pain, splenomegaly and cytopenia and have an indolent clinical course. We describe a case of a women 79 years old who presented with abdominal pain, fever and splenomegaly. Computed tomography demonstrated splenomegaly with an area of low density in the spleen. Only by laparotomy and splenectomy the correct diagnosis was possible. Because of the indolent course of this kind of lymphomas, splenectomy is the main treatment for patients with abdominal pain, splenomegaly and cytopenia. If there is no pain and no cytopenia, the treatment can be only wait and see. Only in case of progression of disease chemotherapy can be employed.
脾边缘区淋巴瘤是起源于B细胞的罕见肿瘤。多见于老年人,通常无症状,可表现为腹痛、脾肿大和血细胞减少,临床病程呈惰性。我们描述了一例79岁女性患者,她出现腹痛、发热和脾肿大。计算机断层扫描显示脾肿大,脾脏有低密度区。只有通过剖腹手术和脾切除术才能做出正确诊断。由于这类淋巴瘤病程呈惰性,脾切除术是腹痛、脾肿大和血细胞减少患者的主要治疗方法。如果没有疼痛和血细胞减少,治疗可以仅采取观察等待。只有在疾病进展的情况下才可以采用化疗。