Vargas P A, Carlos-Bregni R, Mosqueda-Taylor A, Cuairan-Ruidíaz V, Lopes M A, de Almeida O P
Department of Oral Diagnosis - Oral Pathology, University of Campinas, Dental School, Piracicaba, Brazil.
Oral Dis. 2006 Mar;12(2):200-3. doi: 10.1111/j.1601-0825.2005.01163.x.
We report two cases of an uncommon odontogenic lesion, previously described as adenomatoid dentinoma. They were well-circumscribed unilocular radiolucent lesions exhibiting discrete radiopacities, located in the left mandibular third molar region. Microscopically they were composed of odontogenic hard and soft tissues, similar to a dental germ. Dental papilla and dentin were easily identified. Odontogenic epithelium formed adenomatoid-like structures, and by scanning electron microscopy a layer of enamel was seen in contact with the dentin. Based on these clinical, radiographic, histological and electron microscopical features we proposed the diagnosis of adenomatoid odontogenic hamartoma. Treatment consisted of surgical removal, and no recurrence was observed. In our opinion all similar cases previously reported pertain to the same spectrum of this lesion and thus should be named as suggested above. Moreover, ultrastructural observations using 5 microm sections can be useful to better characterize the presence of hard tissues.
我们报告了两例罕见的牙源性病变,此前被描述为腺样牙瘤。它们是边界清晰的单房性透射性病变,伴有离散的阻射性影像,位于左下颌第三磨牙区。显微镜下,它们由牙源性硬组织和软组织组成,类似于牙胚。牙乳头和牙本质易于识别。牙源性上皮形成腺样结构,通过扫描电子显微镜观察可见一层釉质与牙本质接触。基于这些临床、影像学、组织学和电子显微镜特征,我们提出诊断为腺样牙源性错构瘤。治疗方法为手术切除,未观察到复发。我们认为,之前报道的所有类似病例均属于该病变的同一谱系,因此应按上述建议命名。此外,使用5微米切片进行超微结构观察有助于更好地鉴定硬组织的存在。