Hatano Koji, Ichimaru Naotsugu, Takao Tetsuya, Yoshimura Kazuhiro, Okuyama Akihiko, Takakuwa Tetsuya, Aozasa Katsuyuki, Nakata Yuki, Okumoto Yasushi, Hiraoka Hisatoyo
Department of Urology, Osaka University Graduate School of Medicine.
Hinyokika Kiyo. 2006 Jan;52(1):55-8.
A patient with paraganglioma of the urinary bladder is reported. A 65-year-old woman was referred to our hospital with the chief complaint of postvoiding headache, palpitation, and cold sweat. She had has no episodes of hematuria. On laboratory data, mild elevation was found in plasma neuron specific enolase (NSE), urinary noradrenaline and urinary metanephrine. The patient showed hypertension after urination with the elevation of plasma noradrenaline. 131I-MIBG scintigraphy showed abnormal accumulation in the bladder, and no abnormal accumulation in the other lesion. Pelvic magnetic resonance imaging (MRI) revealed a solid tumor of the urinary bladder, measuring 2 cm in diameter. Paraganglioma of the urinary bladder was diagnosed and the tumor was extirpated. The tumor measured 2 x 2 x 1.5 cm, and histopathologically diagnosed as paraganglioma. After extirpation, the patient became free of the postvoiding symptoms, and showed normal catecholamine levels. She has been followed up for 4 months after operation without any evidence of recurrence.
本文报道了一例膀胱副神经节瘤患者。一名65岁女性因排尿后头痛、心悸和冷汗为主诉转诊至我院。她无血尿发作。实验室检查发现血浆神经元特异性烯醇化酶(NSE)、尿去甲肾上腺素和尿间甲肾上腺素轻度升高。患者排尿后出现高血压,血浆去甲肾上腺素升高。131I-MIBG闪烁显像显示膀胱内有异常聚集,其他部位无异常聚集。盆腔磁共振成像(MRI)显示膀胱有一个实性肿瘤,直径2cm。诊断为膀胱副神经节瘤并切除肿瘤。肿瘤大小为2×2×1.5cm,组织病理学诊断为副神经节瘤。切除术后,患者排尿后症状消失,儿茶酚胺水平正常。术后随访4个月,无复发迹象。