Shore S E, Helfert R H, Bledsoe S C, Altschuler R A, Godfrey D A
Department of Otolaryngology, Medical College of Ohio, Toledo 43699.
Hear Res. 1991 Mar;52(1):255-68. doi: 10.1016/0378-5955(91)90205-n.
The origins of extrinsic projections to the guinea pig dorsal and ventral cochlear nuclei were identified by examining the retrograde transport of horseradish peroxidase conjugated to wheatgerm agglutinin following its injection into each of these divisions. Major projections originated in periolivary regions of the superior olivary complex, the contralateral cochlear nucleus and the inferior colliculus. There was no contribution from the nuclei of the lateral lemniscus to these pathways. The heaviest projection from the periolivary regions to both divisions of the cochlear nucleus arose bilaterally in the ventral nucleus of the trapezoid body. The ipsilateral lateral nucleus of the trapezoid body also projected heavily to dorsal and ventral cochlear nucleus. In addition, the ventral cochlear nucleus received a substantial projection from the dorsal aspect of the ipsilateral dorsomedial periolivary nucleus. Projections originating bilaterally in the central nucleus of the inferior colliculus terminated in the deep layers of dorsal cochlear nucleus. These projections appear to be more strongly ipsilateral and specific than those reported in the cat.
通过将与麦芽凝集素结合的辣根过氧化物酶注入豚鼠背侧和腹侧耳蜗核的各个区域，研究其逆向运输，从而确定了到这些区域的外在投射的起源。主要投射起源于上橄榄复合体的橄榄周区域、对侧耳蜗核和下丘。外侧丘系核没有参与这些通路。从橄榄周区域到耳蜗核两个分区的最重投射双侧起源于梯形体腹侧核。同侧梯形体外侧核也大量投射到背侧和腹侧耳蜗核。此外，腹侧耳蜗核从同侧背内侧橄榄周核的背侧接受大量投射。双侧起源于下丘中央核的投射终止于背侧耳蜗核的深层。这些投射似乎比猫中报道的投射更具同侧性和特异性。
