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采用压榨钳法行择期肝切除术后腹腔引流效果的随机临床试验

Randomized clinical trial of the effects of abdominal drainage after elective hepatectomy using the crushing clamp method.

作者信息

Sun H-C, Qin L-X, Lu L, Wang L, Ye Q-H, Ren N, Fan J, Tang Z-Y

机构信息

Liver Cancer Institute and Zhong Shan Hospital, Fudan University, Shanghai 200032, China.

出版信息

Br J Surg. 2006 Apr;93(4):422-6. doi: 10.1002/bjs.5260.

Abstract

BACKGROUND

Abdominal drainage is a standard procedure after hepatectomy, but this practice has been challenged recently.

METHODS

Between September 2004 and March 2005, 120 consecutive patients who had undergone hepatic resection by the same surgical team were randomly allocated into drainage and no drainage groups (60 in each group). Patient characteristics, preoperative liver function, presence of cirrhosis, resection-related factors and postoperative complications were compared between the two groups.

RESULTS

The groups were comparable in terms of demographics, indications for surgery, preoperative liver function test results, presence of cirrhosis, extent of hepatectomy, intraoperative blood loss and requirement for blood transfusion. Symptomatic subphrenic collection and pleural effusion occurred in four patients (7 per cent) who had abdominal drainage and three (5 per cent) who did not. Local wound complications occurred in 17 (28 per cent) and two (3 per cent) patients respectively (P < 0.001). The postoperative hospital stay was similar in the two groups. Multivariate analysis indicated that the presence of cirrhosis and abdominal drainage were independently related to the development of postoperative wound complications.

CONCLUSION

Routine abdominal drainage is unnecessary after elective hepatectomy using the crushing clamp method.

摘要

背景

肝切除术后进行腹腔引流是一种标准操作,但最近这种做法受到了挑战。

方法

在2004年9月至2005年3月期间,由同一手术团队进行肝切除的120例连续患者被随机分为引流组和非引流组(每组60例)。比较两组患者的特征、术前肝功能、肝硬化情况、与切除相关的因素及术后并发症。

结果

两组在人口统计学、手术指征、术前肝功能检查结果、肝硬化情况、肝切除范围、术中失血及输血需求方面具有可比性。有腹腔引流的4例患者(7%)出现有症状的膈下积液和胸腔积液,无腹腔引流的有3例患者(5%)出现。局部伤口并发症分别发生在17例(28%)和2例(3%)患者中(P<0.001)。两组术后住院时间相似。多因素分析表明,肝硬化的存在和腹腔引流与术后伤口并发症的发生独立相关。

结论

使用压榨钳法进行择期肝切除术后无需常规进行腹腔引流。

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