Is there a role for high-frequency ultrasonography in clinical staging of retinopathy of prematurity?
作者信息
Jokl Danny H Kauffinann, Silverman Ronald H, Nemerofiky Sheri L, Kane Steven A, Chiang Michael F, Lopez Robert, Lee Grace
机构信息
Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
出版信息
J Pediatr Ophthalmol Strabismus. 2006 Jan-Feb;43(1):31-5. doi: 10.3928/01913913-20060101-04.
PURPOSE
To compare 20-MHz ultrasonography with ophthalmoscopy in the staging of retinopathy of prematurity (ROP).
METHODS
We used a handheld 20-MHz ultrasound system to examine 38 eyes of 19 neonates who had an indirect ophthalmoscopic examination (diagnosis masked) within 48 hours prior to ultrasonography. Determination of ROP by indirect ophthalmoscopy was compared with independent identification of ultrasonic features indicative of ROP stages.
RESULTS
In masked cases, ultrasonography correctly identified 13 of 18 (72.2% sensitivity) eyes with zone 2, stage 2 ROP or worse and 19 of 20 (95.0% specificity) normal eyes (zone 2, stage 1 ROP or better) (chi-square, 18.4; P < .001).
CONCLUSION
In the neonatal nursery, a 20-MHz handheld ultrasound system may be an effective screening tool to initially identify ROP for further ophthalmoscopic evaluation and management.
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