Zei Paul C, Stevenson William G
Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Heart Rhythm. 2006 Mar;3(3):360-3. doi: 10.1016/j.hrthm.2005.10.022.
Percutaneous entry into the pericardial space allows epicardial catheter mapping and ablation in the electrophysiology laboratory, opening a perspective on cardiac electrophysiology that previously was limited largely to the operating room. Scar-related reentry after myocardial infarction usually involves the subendocardium but in some patients can only be ablated from the epicardium. Epicardial, scar-related reentry also is an important cause of ventricular tachycardia in nonischemic cardiomyopathies. Rare supraventricular tachycardias and idiopathic ventricular tachycardia that cannot be defined from the endocardium sometimes can be ablated from the epicardium. With appropriate precautions the procedural risks are low. Epicardial catheter techniques expand the options for investigating cardiac electrophysiology and treating arrhythmias in humans and may lead to insights into transmural properties influencing repolarization and the genesis of arrhythmias.
经皮进入心包腔可在电生理实验室进行心外膜导管标测和消融,为心脏电生理学开辟了一个新视角,此前该领域很大程度上局限于手术室。心肌梗死后与瘢痕相关的折返通常累及心内膜下层,但在一些患者中只能从心外膜进行消融。心外膜、与瘢痕相关的折返也是非缺血性心肌病室性心动过速的重要原因。一些罕见的室上性心动过速和无法从心内膜明确诊断的特发性室性心动过速有时可从心外膜进行消融。采取适当的预防措施后,手术风险较低。心外膜导管技术扩展了研究人体心脏电生理学和治疗心律失常的选择,并可能有助于深入了解影响复极和心律失常发生的跨壁特性。