一例通过使用猪蛔虫幼虫排泄分泌（ES）抗原诊断出的猪蛔虫内脏幼虫移行症病例。
A case of Ascaris suum visceral larva migrans diagnosed by using A. suum larval excretory-secretory (ES) antigen.
作者信息
Nakamura-Uchiyama Fukumi, Tokunaga Yoshifumi, Suzuki Asahi, Akao Nobuaki, Hiromatsu Kenji, Hitomi Shigemi, Nawa Yukifumi
机构信息
Parasitic Diseases Unit, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan.
出版信息
Scand J Infect Dis. 2006;38(3):221-4. doi: 10.1080/00365540500348952.
A 42-y-old female presented with common cold-like symptoms. Laboratory data showed mild liver dysfunction together with peripheral blood eosinophilia. She was suspected of having a helminthic infection, however parasite eggs or larvae were not detected by repeated stool examinations. Eventually she transpired to have a high IgG antibody titer against excretory-secretary (ES) antigen of Ascaris suum larvae, but not of Toxocara canis larvae, suggesting that she had been suffering from visceral larva migrans (VLM) caused by A. suum. Her sickness improved without any treatment. Current results clearly highlight the usefulness of ES antigens derived from larvae of A. suum for the fine discrimination of VLM caused by A. suum and by T. canis. Application of A. suum derived ES antigens as a diagnostic tool may reveal the distinctive clinical features of VLM caused by A. suum.
一名42岁女性出现类似普通感冒的症状。实验室数据显示轻度肝功能不全以及外周血嗜酸性粒细胞增多。她被怀疑患有蠕虫感染，然而多次粪便检查未检测到寄生虫卵或幼虫。最终发现她针对猪蛔虫幼虫的排泄-分泌（ES）抗原具有高IgG抗体滴度，但针对犬弓首线虫幼虫则没有，这表明她患有由猪蛔虫引起的内脏幼虫移行症（VLM）。她未经任何治疗病情就有所好转。目前的结果清楚地突出了源自猪蛔虫幼虫的ES抗原对于精确区分由猪蛔虫和犬弓首线虫引起的VLM的有用性。将源自猪蛔虫的ES抗原用作诊断工具可能会揭示由猪蛔虫引起的VLM的独特临床特征。
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