Ma Brigette B Y, Chan Anthony T C
Department of Clinical Oncology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Expert Rev Anticancer Ther. 2006 Mar;6(3):383-94. doi: 10.1586/14737140.6.3.383.
Nasopharyngeal carcinoma (NPC) is endemic in Asia and is etiologically associated with the Epstein-Barr virus. Although radiotherapy can cure most patients with early-stage disease, those with advanced disease often develop recurrences following radiotherapy. The past decade has witnessed significant advances in the systemic treatment of advanced NPC. This article reviews the latest literature regarding: combined modality therapy for locoregionally advanced NPC; clinical trials of novel biologic and cytotoxic therapies for metastatic NPC; and disease monitoring with the plasma Epstein-Barr virus DNA assay.
鼻咽癌（NPC）在亚洲呈地方性流行，病因与爱泼斯坦-巴尔病毒有关。尽管放射治疗可治愈大多数早期疾病患者，但晚期疾病患者在放疗后常出现复发。过去十年见证了晚期鼻咽癌全身治疗的重大进展。本文综述了以下方面的最新文献：局部晚期鼻咽癌的综合治疗；转移性鼻咽癌新型生物和细胞毒性疗法的临床试验；以及血浆爱泼斯坦-巴尔病毒DNA检测用于疾病监测。
Zotero 插件