Sakellaridis Nikolaos, Mahera Helen, Pomonis Spiros
Department of Neurosurgery, KAT National Hospital, Kifissia, Attica, Greece.
J Neurosurg Spine. 2006 Feb;4(2):179-82. doi: 10.3171/spi.2006.4.2.179.
The purpose of this report is to demonstrate that synovial sarcoma should be included in the differential diagnosis of tumors originating from the lumbar spine, especially if they show hemangiopericytoma-like pathological characteristics. A synovial sarcoma is a mesenchymal spindle cell tumor that displays variable epithelial differentiation including glandular formation. It is unrelated to a synovium. More than 80% of these lesions arise in the deep soft tissue of the extremities. The tumor frequently arises adjacent to joints or tendon sheaths. The authors describe a young woman with a hemangiopericytoma-like tumor of the lumbar spine. During repeated operation, this lesion was shown to be a synovial sarcoma, which had invaded the dura mater. The tumor metastasized to the mediastinum and the intradural cervical spine and, finally, to the brain and the lungs. To the authors' knowledge, this is the first reported case of a synovial sarcoma originating from the lumbar spine.
本报告的目的是证明滑膜肉瘤应纳入腰椎原发肿瘤的鉴别诊断中，特别是当它们表现出类似血管外皮细胞瘤的病理特征时。滑膜肉瘤是一种间叶性梭形细胞肿瘤，表现出可变的上皮分化，包括腺性形成。它与滑膜无关。超过80%的这些病变发生在四肢深部软组织。肿瘤常发生于关节或腱鞘附近。作者描述了一名患有腰椎类似血管外皮细胞瘤的年轻女性。在反复手术过程中，该病变被证明是滑膜肉瘤，已侵犯硬脑膜。肿瘤转移至纵隔和硬膜内颈椎，最终转移至脑和肺。据作者所知，这是首例源自腰椎的滑膜肉瘤报告病例。
