Healy D, Harris M, Tranter R, Gutting P, Austin R, Jones-Edwards G, Roberts A P
North Wales Department of Psychological Medicine, Hergest Unit, Bangor LL57 2PW, UK.
Br J Psychiatry. 2006 Mar;188:223-8. doi: 10.1192/bjp.188.3.223.
Recent interest in suicide rates in schizophrenia has been considerable.
To establish the lifetime suicide rate from the pre-chlorpromazine era and to compare this with recent lifetime suicide rates for schizophrenia.
We have compared suicide and suicide attempt rates for 741 admissions for schizophrenia and 1303 admissions for psychoses to the North Wales Asylum between 1875 and 1924, with first admissions for psychosis in NorthWest Wales between 1994 and 1998.
The suicide rate in schizophrenia between 1875 and 1924 was 20 per 100 000 hospital years, a lifetime rate of less than 0.5%. The suicide rate for all psychoses was 16 per 100 000 hospital years. Current rates of suicide for schizophrenia and other psychoses appear 20-fold higher.
These findings point to an increase in suicide rates for patients with schizophrenia.
近期对精神分裂症自杀率的关注颇多。
确定氯丙嗪时代之前的终生自杀率,并将其与近期精神分裂症的终生自杀率进行比较。
我们比较了1875年至1924年间北威尔士精神病院741例精神分裂症入院患者和1303例精神病入院患者的自杀及自杀未遂率,以及1994年至1998年间威尔士西北部首次精神病入院患者的情况。
1875年至1924年间,精神分裂症的自杀率为每10万住院年20例,终生率低于0.5%。所有精神病的自杀率为每10万住院年16例。目前精神分裂症和其他精神病的自杀率似乎高出20倍。
这些发现表明精神分裂症患者的自杀率有所上升。