Sonneville R, Lagrange M, Guidoux C, Michel M, Khellaf M, Russel S, Hosseini H
Service de Neurologie, CHU Henri Mondor, Créteil, France.
Rev Neurol (Paris). 2006 Feb;162(2):229-32. doi: 10.1016/s0035-3787(06)75004-4.
In Churg and Strauss syndrome (CSS), three patterns of neurological involvement can be found, including mono or polyneuropathy, encephalopathy and stroke. We report two cases of stroke associated with major hypereosinophilia and cardiac involvement, leading to a diagnosis of CSS. Neurological and general outcome were good under treatment with steroids in combination with cyclophosphamide in one case. Churg and Strauss syndrome must be considered when a stroke is associated with a cardiac involvement and hypereosinophilia.