Lozano José V, Redón Josep, Cea-Calvo Luis, Fernández-Pérez Cristina, Navarro Jorge, Bonet Alvaro, González-Esteban Jorge
Centro de Salud Serrería 2, Valencia, España.
Rev Esp Cardiol. 2006 Feb;59(2):136-42.
Left ventricular hypertrophy (LVH) is the earliest manifestation of cardiac damage in hypertension. Its appearance is associated with a poor cardiovascular prognosis. The objectives of this study were to determine the prevalence of electrocardiographic LVH and to assess the epidemiological characteristics of hypertensive patients receiving primary care.
A cross-sectional multicenter study of hypertensive patients aged 55 years or more was carried out in a primary care setting. Blood pressure was measured using the standard method. Cardiovascular history was determined from medical records and LVH was assessed electrocardiographically using Cornell's criteria.
In total, 15 798 patients (mean age 68.0 years, 55.3% women, and 30.4% with diabetes mellitus) were evaluated. Of these, 3207 (20.3%) had electrocardiographic signs of LVH. The prevalence was higher in males, diabetics, smokers, and patients with high blood pressure or renal or cardiovascular disease. Compared to patients without LVH, those with the condition were older, were more often male, and were more likely to have diabetes or renal or cardiovascular disease. Multivariate analysis showed that LVH was independently associated with advanced age, male gender, diabetes, smoking, poor blood pressure control, and the presence of cardiovascular or renal disease. Blood pressure control was poorer in patients with LVH than in those without it.
The prevalence of electrocardiographic LVH is high, with affected patients being more likely to have diabetes or renal or cardiovascular disease. Moreover, blood pressure control is poor in these patients, and more aggressive pharmacological management is needed.
左心室肥厚(LVH)是高血压患者心脏损害的最早表现。其出现与不良的心血管预后相关。本研究的目的是确定心电图LVH的患病率,并评估接受初级保健的高血压患者的流行病学特征。
在初级保健机构中对55岁及以上的高血压患者进行了一项横断面多中心研究。采用标准方法测量血压。从病历中确定心血管病史,并使用康奈尔标准通过心电图评估LVH。
共评估了15798例患者(平均年龄68.0岁,女性占55.3%,糖尿病患者占30.4%)。其中,3207例(20.3%)有心电图LVH迹象。男性、糖尿病患者、吸烟者以及患有高血压、肾脏疾病或心血管疾病的患者患病率更高。与无LVH的患者相比,有LVH的患者年龄更大,男性更常见,且更有可能患有糖尿病、肾脏疾病或心血管疾病。多变量分析显示,LVH与高龄、男性、糖尿病、吸烟、血压控制不佳以及心血管或肾脏疾病的存在独立相关。有LVH的患者血压控制比无LVH的患者更差。
心电图LVH的患病率很高,患病患者更有可能患有糖尿病、肾脏疾病或心血管疾病。此外,这些患者的血压控制不佳,需要更积极的药物治疗。